Publications

Selected Publications:

P. Picotti, B. Bodenmiller, L.N. Müller, B. Domon and R. Aebersold. Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics. (2009) Cell, 138(4):795-806, 2009.

P. Picotti, O. Rinner, R. Stallmach, F. Dautel, H. Wenschuh, T. Farrah, B. Domon, and R. Aebersold. High-throughput generation of selected reaction-monitoring assays for proteins and proteomes. (2010) Nat. Methods, 7(1):43-6.

P. Picotti, H. Lam, D. Campbell, E.W. Deutsch, H. Mirzaei, J. Ranish, B. Domon, R. Aebersold. A database of mass spectrometric assays for the yeast proteome. (2008) Nat. Methods. 5(11):913-4.

P. Picotti, R. Aebersold, B. Domon. The implications of proteolytic background for shotgun proteomics. (2007) Mol. Cell. Proteomics, 6(9):1589-98.

P. Picotti, G. De Franceschi, E. Frare, B. Spolaore, M Zambonin, F. Chiti, P. Polverino de Laureto and A. Fontana. Amyloid Fibril Formation and Disaggregation of Fragment 1-29 of Apomyoglobin: Insights into the Effect of pH on Protein Fibrillogenesis. J. Mol. Biol. (2007), 367:1237-45.

Other publications:

V. Lange, P. Picotti, B. Domon, R. Aebersold. Selected reaction monitoring for quantitative proteomics: a tutorial. (2008) Mol. Syst. Biol., 4:1-14. Review.

P. Picotti, L. Codutti, O. Marin, S. Dewilde, F. Fogolari, A. Corazza, P. Viglino, L. Moens, G. Esposito, A. Fontana. Conformational stability of neuroglobin helix F – possible effects on the folding pathway within the globin family. (2009) FEBS J., DOI 10.1111/j.1742-4658.2009.07214, Aug 10, 2009. * equally contributing

P. Picotti, S. Dewilde, A. Fago, C. Hundahl, V. De Filippis, L. Moens, A. Fontana. Unusual stability of human neuroglobin at low pH/ Molecular mechanisms and biological significance. FEBS J. 2009 Oct 27.

P. Picotti, A. Marabotti, A. Negro, M. Zambonin, V. Musi, B. Spolaore and A. Fontana. Modulation of the Structural Integrity of Helix F in Apomyoglobin by Single Amino Acid Replacements. Protein Science, (2004) 13: 1572-1585.

B. Bodenmiller, D. Campbell, B. Gerrits, H. Lam, M. Jovanovic, P. Picotti, R. Schlapbach, R. Aebersold. PhosphoPep--a database of protein phosphorylation sites in model organisms. (2008) Nat. Biotechnol., 26(12):1339-40.

S.M. Fendt, J.M. Buescher, F. Rudroff, P. Picotti, N. Zamboni, U. Sauer. Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity. Mol. Syst. Biol., Apr. 13, 2010.

F. Bossi, L. Rizzi, R. Bulla, A. Debeus, C. Tripodo, P. Picotti, E. Betto, P. Macor P, C. Pucillo, R. Wurzner, F. Tedesco. C7 is expressed on endothelial cells as a trap for the assembling terminal complement complex and may exert anti-inflammatory function. (2009) Blood, 113(15):3640-8.

R. Huettenhain, J. Malmstroem, P. Picotti, R. Aebersold. Perspectives of targeted mass spectrometry for protein biomarker verification. Curr Opin Chem Biol. 2009 Oct 7.

E. Bisetto, P. Picotti, E. Bisetto, V. Giorgio, V. Alverdi, I. Mavelli, G. Lippe. Functional and stoichiometric analysis of subunit e in bovine heart mitochondrial F(0)F(1)ATP synthase. (2008) J Bioenerg Biomembr, 40(4):257-67.

V. Musi, B. Spolaore, P. Picotti, M. Zambonin, V. De Filippis and A. Fontana. Nicked Apomyoglobin: a Noncovalent Complex of Two Polypeptide Fragments Comprising the Entire Protein Chain. Biochemistry, (2004) 43: 6230-6240.

A. Fontana, P. Polverino de Laureto, B. Spolaore, E. Frare, P. Picotti, and M. Zambonin. Probing Protein Structure by Limited Proteolysis. Acta Bioch. Pol. (2004): 51(2), 299-321. Review.

A. Kümmel, J.C. Ewald, S.M. Fendt, S.J. Jol, P. Picotti, R. Aebersold, U. Sauer, N. Zamboni and M. Heinemann. Differential glucose repression in common yeast strains in response to HXK2 deletion. FEMS Yeast Res. Jan, 2010.

R. Kiyonami, A. Schoen, A. Prakash, S. Peterman, V. Zabrouskov, P. Picotti, R. Aebersold, A. Huhmer, and B. Domon, Increased selectivity, analytical precision, and throughput in targeted proteomics. Mol Cell Proteomics, Jul 27, 2010.