Publications

Peter Lab Publications 2003 – present

2023

Cereghetti G#, Kissling VM*, Koch LM*, Arm A*, Afanasyev P, Linsenmeier M, Eichmann C, Zhou J, Cao Y, Pfizenmaier DM, Kroschwald S, Wiegand T, Cadalbert R, Böhringer D, Mezzenga R, Arosio P, Riek R, and Peter M#. A conserved mechanism regulates reversible amyloids via pH-sensing regions. Dev. Cell, in revision. https://www.biorxiv.org/content/10.1101/2022.03.21.484600v1. # corresponding authors.

Stier, A., Gilberto, S., Mohamed, W.I., Royal, L.N., Helenius, J., Mikicic, I., Sajic, T., Beli, P., Müller, D.J., Jessberger, S., and Peter, M. (2023) The CUL4B-based E3 ubiquitin ligase regulates mitosis and brain development by recruiting phospho-specific DCAFs. The EMBO Journal, e112847 https://doi.org/10.15252/embj.2022112847.

Mosbacher, M., Lee, S.S., Yaakov, G., Nadal-Ribelles, M., de Nadal, E., van Drogen, F., Posas, F., Peter, M., and, Claassen, M., (2023) Positive feedback induces switch between distributive and processive phosphorylation of Hog1.
Nat Commun,14:2477. doi: 10.1038/s41467-023-37430-y.

Uliana, F., Ciuffa, R., Mishra, R., Fossati, A., Frommelt, F., Keller, S., Mehnert, M., Birkeland, E.S., van Drogen, F., Srejic, N., Peter, M., Tapon, N., Aebersold, R., and Gstaiger, M. (2023) Phosphorylation-linked complex profiling identifies assemblies required for Hippo signal integration.
Molecular Systems Biology e11024. doi: 10.15252/msb.202211024.

2022

Simmler, P., Cortijo, C., Koch, L.M., Galliker, P., Angori, S., Bolck, H.A., Mueller, Ch., Vukolic, A., Mirtschink, P., Christinat, Y., Davidson, N.R., Lehmann, K.V., Pellegrini, G., Pauli, Ch., Lenggenhager, D., Guccini, I., Ringel, T., Hirt, Ch., Marquart, K.F., Schaefer, M., Rätsch, G., Peter, M., Moch, H., Stoffel, M., and Schwank, G., (2022) SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer.
Cell Rep., Aug 23;40(8):111266. doi: 10.1016/j.celrep.2022.111266.

Kissling, V.M., Reginato, G., Bianco, E., Kasaciunaite, K., Tilma, J., Cereghetti, G., Schindler, N., Lee, S.S., Guérois, R., Luke, B., Seidel, R., and Peter, M. (2022) Mre11-Rad50 oligomerization promotes DNA double-strand break repair.
Nat Commun,2;13(1):2374. doi: 10.1038/s41467-022-29841-0.

Mishra, R., Minc, N., and Peter, M. (2022) Cells under pressure: how yeast cells respond to mechanical forces.
Trends in Microbiology, May 5;30: 495-510. doi: 10.1016/j.tim.2021.11.006. 

2021

Schreiber, A., Collins, B.C., Davis, C., Enchev, R.I. , Sedra, A., D'Antuono, R., Aebersold, R., and Peter, M. (2021) Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation.
Mol Cell, Nov 18;S1097-2765(21)00931-X. doi: 10.1016/j.molcel.2021.10.024. 

Mohamed, W.I., Park, S.L., Rabl, J., Leitner, A., Boehringer D., and Peter, M. (2021) The human GID complex engages two independent modules for substrate recruitment.
EMBO Rep., Nov 4;22(11):e52981. doi: 10.15252/embr.202152981. Epub 2021 Oct 14.

Cereghetti, G., Wilson-Zbinden, C., Kissling, V.M., Diether, M., Arm, A., Yoo, H., Piazza, I., Saad, S., Picotti, P., Drummond, D.A., Sauer, U., Dechant, R., and Peter, M. (2021) Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly.
Nat Cell Biol., Oct;23(10):1085-1094. doi: 10.1038/s41556-021-00760-4. Epub 2021 Oct 6.  

2020

Koch, L.M., Birkeland, E.S., Battaglioni, S., Helle, X., Meerang, M., Hiltbrunner, S., Ibáñez, A.J., Peter, M., Curioni-Fontecedro, A., Opitz, I., and Dechant, R. (2020) Cytosolic pH regulates proliferation and tumour growth by promoting expression of cyclin D1.
Nat Metab, 2020 Nov;2(11):1212-1222. doi: 10.1038/s42255-020-00297-0. Epub 2020 Oct 19.  

Birkeland, E.S., Koch, L.M., and Dechant, R., (2020) Another Consequence of the Warburg Effect? Metabolic Regulation of Na+/H+ Exchangers May Link Aerobic Glycolysis to Cell Growth.
Front. Oncol., 18 Aug. doi.org/10.3389/fonc.2020.01561.

Lee, B., Jeong, S.G., Jin, S.H., Mishra, R., Peter, M., Lee, C.S., and Lee, S.S. (2020) Qantitative analysis of yeast MAPK signaling networks and crosstalk using a microfluidic device.
Lab Chip, 2020 Aug 7;20(15):2646-2655. doi: 10.1039/d0lc00203h. Epub 2020 Jun 29.  

Mäeots, M.E., Lee, B.J., Nans, A., Jeong, S.G., Esfahani, M., Ding, S., Smith, D., Lee, C.S., Lee, S.S., Peter, M., and, Enchev, R. (2020) Modular microfluidics enables kinetic insight from time-resolved cryo-EM.
Nat Commun, 2020 Jul 10;11(1):3465. doi: 10.1038/s41467-020-17230-4.

van Drogen, F., Dard, N., Pelet, S., Lee, S.S., Mishra, R., Srejic, N., and, Peter, M. (2020) Crosstalk and spatiotemporal regulation between stress-induced MAP kinase pathways and pheromone signaling in budding yeast.
Cell Cycle, 2020 Jul;19(14):1707-1715. doi: 10.1080/15384101.2020.1779469. Epub 2020 Jun 18.  

Grigaitis, R., Ranjha, L., Wild, P., Kasaciunaite, K., Ceppi, I., Kissling, V., Henggeler, A., Susperregui, A., Peter, M., Seidel, R., Cejka, P., and Matos, J., (2020) Regulatory control of RecQ helicase Sgs1/BLM during meiosis and mitosis.
Dev Cell. 2020 Jun 22;53(6):706-723.e5. doi: 10.1016/j.devcel.2020.05.016. Epub 2020 Jun 5.

You, J.G., Lee, B., Choi, Y., Lee, C.S., Peter, M., Im, S.G., Lee, S.S. (2020) Nanoadhesive layer to prevent protein absorption in a poly(dimethylsiloxane) microfluidic device.
Biotechniques., May 6. doi: 10.2144/btn-2020-0025.

2019

Füzesi-Levi M.G., Fainer, I., Enchev, R.I., Ben-Nissan, G., Levin, Y., Kupervaser, M., Friedlander, G., Salame, T.M., Nevo, R., Peter, M., Sharon, M. (2019) CSNAP, the smallest CSN subunit, modulates proteostasis through cullin-RING ubiquitin ligases.
Cell Death Differ., Jul 31. doi: 10.1038/s41418-019-0392-8.  

Soste, M., Charmpi, K., Lampert, F., Gerez, J.A., van Oostrum, M., Malinovska, L., Boersema, P.J., Prymaczok, N.C., Riek, R., Peter, M., Vanni, S., Beyer, A., and Picotti, Pl. (2019) Proteomics-Based Monitoring of Pathway Activity Reveals that Blocking Diacylglycerol Biosynthesis Rescues from Alpha-Synuclein Toxicity.
Cell Syst., Epub Sep 11. 25;9(3):309-320.e8. doi: 10.1016/j.cels.2019.07.010.  

van Drogen, F., Mishra, R., Rudolf, F., Walczak, M.J., Lee, S.S., Reiter, W., Hegemann, B., Pelet, S., Dohnal, I., Binolfi, A., Yudina, Z., Selenko, P., Wider, G., Ammerer, G., and Peter, M., (2019) Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.
J. Cell Biol., Epub July 17. doi:  10.1083/jcb.201808161.

Gerez, J.A., Prymaczok, N.C., Rockenstein, E., Herrmann, U.S., Schwarz, P., Adame, A., Enchev, R.I., Courtheoux, T., Boersema, P.J., Riek, R., Peter, M., Aguzzi, A., Masliah, E., and Picotti, P. (2019) A cullin-RING ubiquitin ligase targets exogenous alpha-synuclein and inhibits Lewy body-like pathology.
Sci Transl Med., 11(495). doi: 10.1126/scitranslmed.aau6722.

Schmidt, O., Weyer, Y., Baumann, V., Widerin, M.A., Eising, S., Angelova, M., Schleiffer, A., Kremser, L., Lindner, H., Peter, M., Fröhlich, F., and Teis, D. (2019) Endosome and Golgi 1 associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism.
EMBO J., Epub May 27. doi: 10.15252/embj.2018101433.  

2018

Cannavo, E., Johnson, D., Andres, S.N., Kissling, V.M., Reinert, J.K., Garcia, V., Erie, D.A., Hess, D., Thomä, N.H., Enchev, R.I., Peter, M., Williams, R.S., Neale, M.J., and Cejka P. (2018) Regulatory control of DNA end resection by Sae2 phosphorylation.
Nat Commun. Oct 1;9(1):4016. doi: 10.1038/s41467-018-06417-5.

Cereghetti, G., Saad, S., Dechant, R., and Peter, M. (2018) Reversible, functional amyloids: towards an understanding of their regulation in yeast and humans.
Cell Cycle. 17(13):1545-1558. doi: 10.1080/15384101.2018.1480220. Epub 2018 Aug 2.

Lampert, F., Stafa, D., Goga, A., Soste, M.V., Gilberto, S., Olieric, N., Picotti, P., Stoffel, M., and Peter, M. (2018) The multi-subunit GID/CTLH E3 ligase promotes proliferation and targets the transcription factor Hbp1 for degradation.
Elife. Jun 18;7. pii: e35528. doi: 10.7554/eLife.35528.  

Grignaschi, E., Cereghetti, G., Grigolato, F., Kopp, M., Caimi, S., Faltova, L., Saad, S., Peter, M., and Arosio, P. (2018) A hydrophobic low complexity region regulates aggregation of the yeast pyruvate kinase Cdc19 into amyloid-like aggregates in vitro.
J Biol Chem. May 31. pii: jbc.RA117.001628. doi: 10.1074/jbc.RA117.001628. [Epub ahead of print].

2017

Mishra, R., van Drogen, F., Dechant, R., Oh, S., Jeon, N.L., Lee, S.S., and Peter, M. (2017) Protein kinase C and calcineurin cooperatively mediate cell survival under compressive mechanical stress.
PNAS, 114, 51, 13471–13476. doi: 10.1073/pnas.1709079114.

Jin, S.H., Lee, S.S., Lee, B., Jeong, S.G., Peter, M., and Lee C.S. (2017) A programmable static droplet array for the analysis of cell-cell communication in a confined microenvironment.
Anal Chem., 89, 9722-9729. doi: 10.1021/acs.analchem.7b01462.  

Michel, A.H., Hatakeyama, R., Kimmig, P., Arter, M., Peter, M., Matos, J., De Virgilio, C., Kornmann, B. (2017) Functional mapping of yeast genomes by saturated transposition.
Elife. 2017 May 8;6. pii: e23570. doi: 10.7554/eLife.23570.

Saad, S., Cereghetti, G., Feng, Y., Picotti, P., Peter, M.*, and Dechant, R.* (2017) Reversible protein aggregation is a protective mechanism to ensure cell cycle restart after stress.
Nature Cell Biology, Oct;19(10):1202-1213. doi: 10.1038/ncb3600. Epub 2017 Aug 28. *corresponding authors.

Janouskova, H., El Tekle, G., Udeshi, N.D., Ulbricht, A., Rinaldi, A., Bernasocchi, T., Civenni, G., Losa, M., Svinkina, T., Bielski, C.M., Kryukov, G.V., Dai, X., Gan, W., Wei, W., Bellini, E., Wild, P.J., Catapano, C.V., Peter, M., Carr, S.A., Garraway, L.A., and Theurillat, J.-P. (2017) Opposing effects of Cancer-type specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.
Nature Medicine, Aug 14. doi: 10.1038/nm.4372.

Gilberto, S. and Peter, M. (2017) Dynamic ubiquitin signaling in cell cycle regulation.
Journal of Cell Biology, Aug 7;216(8):2259-2271. doi: 10.1083/jcb.201703170.

Hegemann, B. and Peter, M. (2017) Local sampling paints a global picture.
Bioessays, 2017 May 26. doi: 10.1002/bies.201600134. [Epub ahead of print] Review

Abreu, S., Kriegenburg, F., Gómez-Sánchez, R., Mari, M., Sanchez-Wandelmer, J., Skytte Rasmussen, M., Soares Guimaraes, R., Zens, B., Schuschnig, M., Hardenberg, R., Peter, M., Johansen, T., Kraft, C., Martens, S., and Reggiori, F. (2017) Conserved Atg8-recognition sites mediate Atg4 association to autophagosomal membranes and Atg8 deconjugation.
EMBO Rep. 2017 May;18(5):765-780. doi: 10.15252/embr.201643146. Epub 2017 Mar 22

Lampert, F., Brodersen, M.L., Peter, M. (2017) Guard the guardian: A CRL4 ligase stands watch over histone production.
Nucleus, Jan 10:1-10. doi: 10.1080/19491034.2016.1276143. [Epub ahead of print]

2016

Fumagalli, F., Noack, J., Bergmann, T., Cebollero, E., Pisoni, G.B., Fasana, E., Fregno, I., Galli, C., Loi, M., Soldà, T., D'Antuono, R., Raimondi, A., Jung, M., Melnyk, A., Schorr, S., Schreiber, A., Simonelli, L., Varani, L., Wilson-Zbinden, C., Zerbe, O., Hofmann, K., Peter, M., Quadroni, M., Zimmermann, R. and Molinari, M. (2016) Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery.
Nat Cell Biol. Nov;18(11):1173-1184. doi: 10.1038/ncb3423. Epub 2016 Oct 17.

Piwko, W., Mlejnkova, L.J., Mutreja, K., Ranjha, L., Stafa, D., Smirnov, A., Brodersen, M.L., Zellweger, R., Sturzenegger, A., Janscak, P., Lopez, M., Peter, M., and Ceijka, P. (2016) The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress.
EMBO J., 35(23):2584-2601.

Courthéoux, T., Enchev, R., Lampert, F., Gerez, J.A., Beck, J., Picotti, P., Sumara, I., and Peter, M. (2016) Cortical dynamics during cell motility are governed by CUL3KLHL21 E3 ubiquitin ligase.
Nat Commun, 19;7:12810. doi: 10.1038/ncomms12810.

Ferretti, L.P., Himmels, S.F., Trenner, A., Walker, C., von Aesch, C., Eggenschwiler, A., Murina, O., Enchev, R.I., Peter, M., Freire, R., Porro, A., Sartori, A.A. (2016) Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection.
Nat Commun. Aug 26;7:12628. doi: 10.1038/ncomms12628.  

Brodersen, M.L., , Lampert, F., Barnes, C.A., Soste, M., Piwko, W., and Peter, M. (2016) CRL4^WDR23-mediated SLBP ubiquitylation ensures histone supply during DNA replication.
Mol. Cell, 62(4):627-35. doi: 10.1016/j.molcel.2016.04.017.

Mosadeghi, R., Reichermeier, K., Winkler, M., Schreiber, A., Reitsma, J.M., Zhang, Y., Stengel, F., Cao, J., Kim, M., Sweredoski, M.J., Hess, S., Leitner, A., Aebersold, R., Peter. M.*, Deshaies, R.J.*, and Enchev, R.I.* (2016) Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle. *corresponding authors.
Elife, 5pii:e12102. doi: 10.7554/eLife.12102.

Gschweitl, M., Ulbricht, A., Barnes, C.A., Enchev, R.I., Stoffel-Studer, I., Meyer-Schaller, N., Huotari, J., Yamauchi, Y., Greber, U.F., Helenius, A.*, and Peter, M.* (2016) A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. *corresponding authors.
Elife, 5:e13841. doi: 10.7554/eLife.13841.

Buser, R., Kellner, V., Melnik, A., Wilson-Zbinden, C., Schellhaas, R., Kastner, L., Piwko, W., Dees, M., Picotti, P., Maric, M., Labib, K., Luke, B., and Peter, M. (2016) The Replisome-Coupled E3 Ubiquitin Ligase Rtt101^Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress.
PLoS Genet., 12(2):e1005843. doi: 10.1371/journal.pgen.1005843.

2015

Orthwein, A., Noordermeer, S.M., Wilson, M.D., Landry, S., Enchev, R.I., Sherker, A., Munro, M., Xia, B., Peter, M., and Durocher, D. (2016) Cell cycle-regulated assembly of the BRCA1-PALB2-BRCA2 complex controls homologous recombination.
Nature, 528(7582):422-6. doi: 10.1038/nature16142.

Ryu, H., Chung, M., Dobrzyński, M., Fey, D., Blum, Y., Lee, S. S., Peter, M., Kholodenko, B. N., Jeon N. L., and Pertz, O. (2015)
Frequency modulation of ERK activation dynamics rewires cell fate.
Mol Syst Biol. 11, 838. doi: 10.15252/msb.20156458.

Hegemann, B., Unger, M., Lee, S.S., Stoffel-Studer, I., van den Heuvel, J., Pelet, S., Koeppl, H., and Peter, M. (2015)
A Cellular System for Spatial Signal Decoding in Chemical Gradients.
Dev Cell, 35, 1-13. doi:10.1016/j.devcel.2015.10.013.

Kanfer, G., Courthéoux, T., Peterka, M., Meier, S., Soste, M., Melnik, A., Reis, K., Aspenström, P., Peter, M., Picotti, P., and Kornmann, B. (2015)
Mitotic redistribution of the mitochondrial network by Miro and Cenp-F.
Nat Commun. 6, 8015. doi: 10.1038/ncomms9015.

Oliveira, A.P., Dimopoulos, S., Busetto, A.G., Christen, S., Dechant, R., Falter, L., Haghir Chehreghani, M., Jozefczuk, S., Ludwig, C., Rudroff, F., Schulz, J.C., González Seviné, A., Soulard, A., Stracka, D., Aebersold, R., Buhmann, J.M., Hall, M.N., Peter, M., Sauer, U., and Stelling, J. (2015)
Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptome.
Mol Syst Biol. 11(4):802. doi: 10.15252/msb.20145475.

Mouysset, J., Gilberto, S., Meier, M.G., Lampert, F., Belwal, M., Meraldi, P., and Peter, M. (2015)
CRL4RBBP7 is required for efficient CENP-A deposition at centromeres.
J Cell Sci, 128 (9) 1732-45.

Sharifian, H., Lampert, F., Stojanovski, K., Regot, S., Vaga, S., Buser, R., Lee, S.S., Koeppl, H., Posas, F., Pelet, S., and Peter, M. (2015)
Parallel feedback loops control the basal activity of the HOG MAPK signaling cascade.
Integr. Biol., 7 (4), 412-22. 

2014

Vaga, S., Bernardo-Faur, M., Cokelaer, T., Maiolica, A., Barnes, CA., Gillet, L.C., Hegemann, B., van Drogen, F., Sharifian, H., Klipp, E., Peter, M., Saez-Rodrigue,z J., and Aebersold, R. (2014)
Phosphoproteomic analyses reveal novel cross-modulation mechanisms between two signaling pathways in yeast.
Mol Syst Biol., 10:767. doi: 10.15252/msb.20145112.

Wilson, C., da Silveira dos Santos, A.X., Stoffel-Studer, I., van der Vaart, A., Hofmann, K., Reggiori, F., Riezman, H., Kraft, C., and Peter, M. (2014)
Autophagy competes for a common phosphatidylethanolamine pool with major cellular PE-consuming pathways in Saccharomyces cerevisiae.
Genetics, 199 (2), 475-85.

Birol, M., Enchev, R.I., Padilla, A., Stengel, F., Aebersold, R., Betzi, S., Yang, Y., Hoh, F., Peter, M., Dumas C., Echalier, A., and Papaleo, E., (2014)
Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer.
PLoS ONE, 9, 8, e105688.

Lee, S.S., Pelet, S., Peter, M., and Dechant, R. (2014)
A rapid and effective vignetting correction for quantitative microscopy.
RSC Advances, 4, 95, 52727-52733.

Dechant, R., and Peter, M. (2014)
Cytosolic pH: a conserved regulator of cell growth?
Molecular & Cellular Oncology, e969643.

Dechant, R., Saad, S., Ibáñez, J., and Peter, M., (2014),
Cytosolic pH regulates cell growth through distinct GTPases, Arf1 and Gtr1, to promote Ras/PKA and TORC1 activity.
Mol. Cell, 55(3), 409-21.

Zechner, C., Unger, M., Pelet, S., Peter, M., and Koeppl, H. (2014)
Pooling single-cell recordings: Scalable inference through heterogeneous kinetics.
Nature Methods, 11(2), 197-202.

Papinski, D., Schuschnig, M., Reiter, W., Wilhelm, L., Barnes, C., Majolica, A., Hansmann, I., Pfaffenwimmer, T., Kijanska, M., Stoffel,  I., Lee, S.S., Brezovich, A., Hua Lou, J., Turk, B.E., Aebersold R., Ammerer, G., Peter, M., and Kraft, C., (2014),
Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase.
Mol. Cell, 53, 471-83.

Walczak, M.J., Samatanga, B., van Drogen, F., Peter, M., Jelesarov, I., and Wider, G., (2014)
The RING domain of the scaffold protein Ste5 adopts a molten globular character with high thermal and chemical stability: an NMR study.
Angew. Chem. Int. Ed., 53, 1320-1323.

2013

Dechant, R., and Peter, M., (2013)
Cytosolic pH regulated by glucose promotes V-ATPase assembly. (in: Handbook of H⁺-ATPases)
S. Nakamura, Editor, Pan Stanford Publishing Pte Ltd., ISBN 978-981-4411-91-2

Schreiber, A., and Peter, M., (2013)
Substrate Recognition in Selective Autophagy and the Ubiquitin Proteasome System.
BBA - Molecular Cell Research, 1843, 163-181.

Saad, S., Peter, M., and Dechant, R. (2013)
In scarcity and abundance: metabolic signals regulating cell growth.
Physiology (Bethesda), 28, 298-309.

Rezgui, V.A.N.*, Tyagi, K.*, Ranjan, N.*, Konevega A.L., Mittelstaet, J., Rodnina, M.V., Peter, M., Pedrioli, P.G.A. (2013)
tRNA tK^UUU, tQ^UUG, and tE^UUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding. 
PNAS, 110, 30, 12289-12294. *equal contribution

Beck, J., and Peter, M. (2013)
Regulating PLK1 dynamics by Cullin3/KLHL22-mediated ubiquitylation.
Cell Cycle, 12, 2528-2529.

Beck, J.*, Maerki, S.*, Posch, M., Metzger, T., Persaud, A., Scheel, H., Hofmann, K., Rotin, D., Pedrioli, P., Swedlow, J.R., Peter, M., and Sumara, I. (2013)
Ubiquitylation-dependent localization of PLK1 in mitosis.
Nat. Cell. Biol., 15 (4), 430-9.

Kijanska, M., and Peter, M. (2013)
Atg1 kinase regulates early and late steps during autophagy.
Autophagy, 9, 2, 249-251.

2012

Bhaskaran, N., van Drogen, F., Ng, H.F., Kumar, R., Ekholm-Reed, S., Peter, M., Sangfelt, O., and Reed, S.I. (2012)
Fbw7a and Fbw7g Collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation.
Mol Cell Biol. 33, 85-97. 

Pelet, S., Dechant, R., Lee, S.S., van Drogen, F., and Peter, M. (2012)
An integrated image analysis platform to quantify signal transduction in single cells.
Integrative Biology, 4, 10, 1274-1282.

Enchev, R., Scott, D., da Fonseca, P., Monda, J., Schreiber, A., Schulman, B. A., Peter, M., and Morris, E. (2012)
Structural basis for a reciprocal regulation between SCF and CSN.
Cell Reports, 2, 3, 616-627.

Kraft, C.*, Kijanska, M.*, Kalie, E., Siergiejuk, E., Lee, S. S., Semplicio, G., Stoffel, I., Brezovich, A., Verma, M., Hansmann, I., Ammerer, G., Hofmann, K., Tooze, S. A. and Peter M. (2012)
Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy.
EMBO J., 31, 18, 3691-3703, *equal contribution.

Hubner, M., and Peter, M. (2012)
Cullin-3 and the endocytic system
Cellular Logistics, 2, 166-168.

Zechner, C., Ruess, J., Krenn, P., Pelet, S., Peter, M., Lygeros, J., and Koeppl, H. (2012)
Moment-Based Inference Predicts Bimodality in Transient Gene Expression.
PNAS, 109, 21, 8340-8345.

Lee, S. S., Horvath, P., Pelet, S., Hegemann, B., Lee, L. P., and Peter, M. (2012)
Quantitative and Dynamic Assay of Single Cell Chemotaxis.
Integrative Biology, 4, 4, 381-390.

Huotari, J. , Meyer-Schaller, N., Hubner, M., Stauffer, S., Katheder, N., Horvath, P., Mancini, R., Helenius, A., and Peter, M. (2012) Cullin-3 regulates late endosome maturation.
PNAS, 109, 3, 823-828.

2011

Pelet, S., and Peter, M. (2011)
Dynamic processes at stress promoters regulate the bimodal expression of HOG response genes.
Commun. Integr. Biol., 4, 6.

Sole, C., Nadal-Ribelles, M., Kraft, C., Peter, M., Posas, F., and de Nadal, E. (2011)
Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress.
EMBO J., 30, 16, 3274-3283.

Zechner, C., Ganguly, A., Pelet, S., Peter, M., and Koeppl, H. (2011)
Accounting for extrinsic variability in the estimation of stochastic rate constants.
Int. J. Robust. Nonlinear Control, 22, 10, 1103-1119.

Rabut, G., Le Dez, G., Verma, R., Makhnevych, T., Knebel, A., Kurz, T., Boone, C., Deshaies, R., and Peter, M. (2011)
The TFIIH subunit Tfb3 regulates cullin neddylation.
Mol. Cell, 43, 488-495.

Piwko, W., Buser, R., and Peter, M. (2011)
Rescuing stalled replication forks MMS22L-TONSL, a novel complex for DNA replication fork repair in human cells.
Cell Cycle, 10, 1703-1705.

Pelet, S., Rudolf, F., Nadal-Ribelles, M., de Nadal, E., Posas, F. and Peter, M. (2011)
Transient activation of the HOG MAPK pathway regulates bimodal gene expression.
Science, 332, 732-735.

Pelet, S., and Peter M. (2011)
Fluorescent-based quantitative measurements of signal transduction in single cells.
Chapter 17 of Koeppl, H. et al. (eds.)
Design and Analysis of Biomolecular Circuits: Engineering Approaches to Systems and Synthetic Biology, Springer, 369-393.

Dechant, R., and Peter, M. (2011)
The N-terminal domain of the V-ATPase subunit "a" is regulated by pH in vitro and in vivo.
Channels, 5, 1, 1-5.

2010

Bodenmiller, B., Wanka, S., Kraft, C., Urban, J., Campbell, D., Pedrioli, P., Gerrits, B., Picotti, P., Lam, H., Vitek, O., Brusniak, M.Y., Roschitzki, B., Zhang, C., Schlapbach, R., Shokat, K., Colman-Lerner, A., Nesviszskii, A.I., Peter, M., Loewith, R., Mering, C.v., Aebersold, R. (2010)
Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Pertubations of Kinases and Phosphatases in Yeast.
Science Signaling, 3, rs4.

Piwko, W., Olma, M.H., Held, M., Bianco, J., Pedrioli, P., Hofmann, K., Pasero, P., Gerlich, D.W., and Matthias Peter (2010) RNAi-based screening identifies the Mms22L – Nfkbil2 complex as a novel regulator of DNA replication in human cells.
EMBO J., 29, 4210-4222.

Kijanska, M., Dohnal, I., Reiter, W., Kaspar, S., Stoffel, I., Ammerer, G., Kraft, C., and Peter, M. (2010)
Activation of Atg1 kinase in autophagy by regulated phosphorylation.
Autophagy, 6, 1168-1178.

Burschowsky, D., Rudolf, F., Rabut, G., Herrmann, T., Peter, M., and Wider, G. (2010)
Structural analysis of the conserved ubiquitin-binding motifs (UBMS) of the translation polymerase IOTA in complex with ubiquitin.
J. Biol. Chem.,286 (2), 1364-1373.

Kraft, C., Peter, M., and Hofmann, K. (2010)
Selective autophagy: ubiquitin recognition and beyond.
Nature Cell Biology, 12, 836-841.

Maerki, S., Beck, J., Sumara, I., and Peter, M., (2010)
Finding the midzone: the role of ubiquitination for CPC localization during anaphase.
Cell Cycle - 9 (15), 2921-2922.

Held, M., Schmitz, M.H.A., Fischer, B., Walter, T., Neumann, B., Olma, M.H., Peter, M., Ellenberg, J., and Gerlich, D.W. (2010) CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging.
Nature Methods - 7 (9), 747-754.

Dechant, R., Binda, M., Lee, SS., Pelet, S., Winderickx, J., and Peter, M. (2010)
Cytosolic pH is a second messenger for glucose and regulates the PKA pathway via V-ATPase.
EMBO J. , 29 (15), 2515-2526.

Schaber, J., Adrover, M.A., Eriksson E., Pelet, S., Petelenz, E., Klein, D., Posas, F., Goksör, M., Peter, M., Hohmann, S., Klipp, E. (2010)
Biophysical properties of Saccharomyces cerevisiae and their relation to HOG pathway activation.
European Biophysics Journal - 39 (11), 1547-56.

2009

Chang, M., Luke, B., Kraft, C., Li, Z., Peter, M., Lingner, J., and Rothstein R., (2009)
Telomerase is essential to alleviate Pif1-induced replication stress at telomeres.
Genetics , 183, 779-79.

Siergiejuk, E., Scott, D.C., Schulman, B.A., Hofmann, K., Kurz, T., Peter, M. (2009)
Cullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharamyces cerevisiae.
EMBO J., 28, 3845-56.

Maerki, S., Olma, M.H., Staubli, T., Steigemann, P., Gerlich D.W., Quadroni, M., Sumara, I., Peter, M. (2009)
The Cul3-KLHL21 E3 ubiquitin ligase targets Aurora B to midzone microtubules in anaphase and is required for cytokinesis.
J. Cell Biol., 187, 791-800.

Meyer-Schaller, N., Chou, Y.C., Sumara, I., Martin, D.D., Kurz, T., Katheder, N., Hofmann, K., Berthiaume, L.G., Peter, M. (2009)
The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes.
PNAS, 106, 12365-12370.

Deplazes, A., Möckli, N, Luke B., Auerbach, D., and Peter M. (2009)
Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control.
EMBO J., 28, 1429-41.

Kraft, C., Reggiori, F. and Peter, M. (2009)
Selective types of autophagy in yeast.
Biochim Biophys Acta, 1793, 1404-1412.

Leidel, S.*, Pedrioli, P.G.A.*, Bucher, T., Brost, R., Costanzo, M., Schmidt, A., Aebersold, R., Boone, C., Hofmann, K. and Peter, M. (2009)
Ubiquitin-related modifier Urm1 acts as a sulfur-carrier in thiolation of eukaryotic tRNA.
Nature, 458, 228-232. *equal contribution

Olma, M. H.*, Roy, M.*, Le Bihan, T., Sumara, I., Maerki, S., Larsen, B., M. Quadroni, M., Peter, M., Tyers, M., and L. Pintard (2009)
An interaction network of the mammalian Cop9/signalosome identifies DDA1 as a core subunit of multiple CUL4-based E3-ligases.
J. Cell Science, 122, 1035-1044. *equal contribution.

2008

Pedrioli, P.G., Leidel, S., Hofmann, K. (2008)
Urm1 at the crossroad of modifications. ‘Protein Modifications: Beyond the Usual Sespects’ Review Series.
EMBO Rep., 12, 1196-202.

Dechant, R., and Peter, M. (2008)
Nutrient signals driving cell growth.
Current Opinion of Cell Biology, 20, 678-687.

Rabut, G. and Peter, M. (2008)
Function and regulation of protein neddylation.
EMBO Rep., 9, 969-976.

Kraft, C. and Peter, M. (2008)
Is Rsp5p involved in the regulation of ribophagy?
Autophagy, 4, 838-840.

Zaidi, I.W.*, Rabut, G.*, Poveda, A., Scheel, H., Malmström, J., Ulrich, H., Hofmann, K., Pasero, P., Peter, M., and Luke, B. (2008)
Rtt101p and Mms1p form a Cul4Ddb1-like ubiquitin ligase, which promotes replication through damaged DNA.
EMBO Rep., 10, 1034-40. *equal contribution

Kraft, C., Deplazes, A., Sohrmann, M., Peter, M. (2008)
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease.
Nature Cell Biology, 10, (5), 602-610.

Kurz, T., Chou, Y.-C., Willems, A., Meyer-Schaller, N., Hecht, M.-L., Tyers, M., Peter, M. and Sicheri, F. (2008)
Dcn1 Functions as a Scaffold-Type E3 Ligase for Cullin Neddylation.
Mol. Cell, 29, 23-35.

Rudolf, F., Pelet, S., and Peter, M., (2008)
Regulation of MAPK signalling in yeast.
Topics in Current Genetics, 20, Stress-Activated Protein Kinases, Posas, F., and Nebrada, A.R. (Eds).

Demmel, L., Gravert, M., Ercan, E., Habermann, B., Müller-Reichert, T., Kukhtina, V., Haucke, V., Baust, T., Sohrmann, M., Kalaidzidis, Y., Klose, Ch., Beck, M., Peter, M. and Walch-Solimena, Ch. (2008)
The Clathrin Adaptor Gga2p Is a Phosphatidylinositol 4-phosphate Effector at the Golgi Exit.
Mol Biol Cell, 19, 1991-2002.

Sumara, I., Maerki, S. and Peter, M. (2008)
E3 ubiquitin ligases and mitosis: embracing the complexity.
Trends Cell Biology, 18, (2), 84-94.

2007

Luke, B., Azzalin, C., Hug, N., Deplazes, A., Peter, M. and Lingner, J. (2007)
Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay.
Nucleic Acids Res, 35, (22), 7688-7697.

Sumara, I. and Peter, M., (2007)
A Cul3-Based E3 Ligase Regulates Mitosis and is Required to Maintain the Spindle Assembly Checkpoint in Human Cells.
Cell Cycle, 6, 24.

Roberts, T., Waris Zaidi I., Vaisica, J., Peter, M. and Brown, G. (2007)
Regulation of Rtt107 Recruitment to Stalled DNA Replication Forks by the Cullin Rtt101 and the Rtt109 Acetyltransferase.
Mol Biol Cell, 19, 171.180.

Knaus, M., Pelli-Gulli, M., van Drogen, F., Springer, S., Jaquenoud, M., and Peter, M. (2007)
Phosphorylation of Bem2p and Bem3p may contribute to local activation of Cdc42p at bud emergence.
EMBO J., 26, 4501-4513.

Luke-Glaser, S., Pintard, L., Tyers, M. and Peter, M. (2007)
The AAA-ATPase FIGL-1 controls mitotic progression, and its levels are regulated in the C. elegans germ line by the CUL-3MEL-26 E3-ligase.
J. Cell Science, 120, 3179-87.

Kuepfer, L., Peter, M., Sauer, U., and Stelling J., (2007)
Ensemble modeling for analysis of cell signaling dynamics.
Nature Biotechnology, 25, 9, 1001-6.

Moeckli N., Deplazes, A., Hassa P.O., Zhang Z., Peter, M., Hottiger, M.O., Stagljar, I., and Auerbach D. (2007)
A yeast split-ubiquitin based cytosolic screening system (cytoY2H) to detect interactions between transcriptionally active proteins.
Biotechniques, 42, 1-5.

Sumara, I., Quadroni, M., Frei, C., Olma, M., Sumara, G., Ricci, R., and Peter, M., (2007)
A Cul3-based E3-ligase is required to remove Aurora B from mitotic chromosomes, thereby regulating mitotic progression and completion of cytokinesis in human cells.
Developmental Cell, 12, 887-900.

Zapater, M., Sohrmann, M., Peter, M., Posas, F., de Nadal, E., (2007)
Selective requirement for SAGA in Hog1-mediated gene expression depending on the severity of the external osmostress conditions.
Mol. Cell. Biol., 27, 3900-10.

Luke-Glaser, S., Roy, M., Larsen, B., Le Bihan, T., Metalnikov, P., Tyers, M., Peter, M., and Pintard, L. (2007)
CIF-1, a shared subunit of the COP9/Signalosome and eIF3 complexes regulates MEL-26 levels in the C. elegans embryo.
Mol. Cell. Biol., 27, 4526-40.

Zumbuehl, A., Stano, P., Sohrmann, M., Peter, M., Walde, P. and Carreira E.M., (2007),
A novel strategy for bioconjugation: synthesis and preliminary evaluation with amphotericin B.
Org. Biomol. Chem., 5, 1339-42.

2006

Blake, D., Luke, B., Kanellis, P., Jorgensen, P., Goh, Th., Penfold, S.,Breitkreutz, B.-J., Durocher, D., Peter, M. and Tyers, M., (2006)
The F-box protein Dia2 overcomes replication impedance to promote genome stability in Saccharamyces cerevisiae.
Genetics, 174, 1709-27.

Luke, B., Versini, G., Jaquenoud, M., Zaidi, I.W., Kurz, T., Pintard, L., Pasero, Ph. and Peter, M. (2006)
The cullin Rtt101p Promotes Replication Fork Progression through Damaged DNA and Natural Pause Sites.
Curr.Biol., 16, 786-792.

Dard, N. and Peter, M. (2006)
Scaffold proteins in MAP kinase signaling: more than simple passive activation platforms.
BioEssays, 28, 146-156.

2005

Bienko, M., Green, C.M., Crosetto, N., Rudolf, F., Zapart, G., Coull, B., Kannouche, P., Wider, G., Peter, M., Lehmann, A.R., Hofmann, K. and Dikic, I. (2005)
Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis.
Science, 310, 1821-1824.

Luke-Glaser, S., Pintard, L., Lu, Ch., Mains, P.E., and Peter, M., (2005)
The BTB-Protein MEL-26 Promotes Cytokinesis in C. elegans by a CUL-3-Independent Mechanism.
Curr. Biol., 15, 1605-1615.

Knaus, M., Cameroni, E., Pedruzzi, I., Tatchell, K., De Virgilio, and Peter, M. (2005)
The Bud14p-Glc7p complex functions as a cortical regulator of dynein in budding yeast.
EMBO J., 24, 3000-3011.

Kurz, T., Ozlü, N., O’Rourke, S., Rudolf, F., Luke, B., Hyman, A.A., Bowerman, B., and Peter, M. (2005)
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.
Nature, 435, 1257-61.

Blondel, M., Bach, S. Bamps, S., Dobbelaere, J., Wiget, P., Longaretti, C., Barral, Y., Meijer, M., and Peter, M. (2005)
Degradation of the PCH-protein Hof1 by SCFGrr1 is important for proper actomyosin ring contraction during cytokinesis in yeast.
EMBO J., 24, 1440-1452.

2004

Vaga, S., Bernardo-Faura, M., Cokelaer, T., Maiolica, A., Barnes, C.A., Gillet, L.C., Hegemann, B., van Drogen, F., Sharifian, H., Klipp, E., and Peter, M. (2014)
Phosphoproteomic analyses reveal novel cross-modulation mechanisms between two signaling pathways in yeast.
Mol Syst Biol, 10, 767-767.

Pintard, L., Willems, A., and Peter, M. (2004)
Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family.
EMBO J., 23, 1681-7.

Lafourcade, L., Galan, J.-M., Gloor, Y., Hagenauer-Tsapis, R., and Peter, M. (2004)
The GAP Gyp1p is required for recycling of internalized membrane material by inactivation of the Rab/Ypt-GTPase Ypt1p.
Mol. Cell. Biol., 24, 3815-3826.

VanDrogen, F., and Peter, M. (2004)
Revealing protein dynamics by photobleaching techniques.
Methods in Mol. Biol. 284, 289-308.

Shimada, Y., Wiget, P., Gulli, M.-P., Bi, E. and Peter, M. (2004)
Regulation of the nucleotide exchange factor Cdc24p by auto-inhibition.
EMBO J., 23, 1051-62.

Wiget, P., Shimada, Y., Butty, A.C. and Peter, M. (2004)
Site-specific activation of the nucleotide exchange factor Cdc24p by the scaffold protein Far1p during yeast mating.
EMBO J., 23, 1063-74.

VanDrogen-Petit, A., Zwahlen, C., Peter, M., and Bovin, A. (2004).
Insight into molecular interactions between two PB1 domains.
J. Mol. Biol., 336, 1195-1210.

Aouida M, Pagé, N, Peter, M., and Dindial, R. (2004)
A genome-wide screen in Saccharomyces cerevisiae reveals altered transport as a mechanism of resistance to anticancer drug bleomycin.
Cancer Research, 64, 1102-1109.

Tong, A.H., Lesage, G., Bader, G.D., Ding, H., Xu, H., Xin, X., Young, J., Berriz, G.F., Brost, R.L., Chang, M., Chen, Y., Cheng, X., Chua, G., Friesen, H., Goldberg, D.S., Haynes, J., Humphries, C., He, G., Hussein, S., Ke, L., Krogan, N., Li Z., Levinson, J.N., Lu, H., Menard, P., Munyana, C., Parsons, A.B., Ryan, O., Tonikian, R., Roberts, T., Sdicu, A.M., Shapiro, J., Sheikh, B., Suter, B., Wong, S.L., Zhang, L.V., Zhu, H., Burd, C.G., Munro, S., Sander, C., Rine, J., Greenblatt, J., Peter, M., Bretscher, A., Bell, G., Roth, F.P., Brown, G.W., Andrews, B., Bussey, H., Boone, C., (2004)
Global mapping of the yeast genetic interaction network.
Science, 303, 808-813.

2003

Sohrmann, M. and Peter, M. (2003)
Polarising without a C(l)ue.
Trends Cell Biol., 13, 526-533.

Pintard, L. and Peter, M. (2003)
Cdc34: cycling on and off the SCF.
Nat. Cell. Biol., 5, 856-857.

Gstaiger, M., Luke, B., Hess, D., Oakeley, E., Wirbelauer, C., Blondel, M., Mestan, J., Vigneron, M., Peter, M. and Krek, W. (2003)
Control of nutrientsensitive transcription programs by the unconventional prefoldin URI1.
Science, 302, 1208-1212.

Pintard, L. Willis, J., Willems, A., Johnson, J., Srayko, M., Kurz, T., Glaser, S., Mains, P., Tyers, M., Bowerman, B. and Peter, M. (2003)
The BTB-containing protein MEL-26 functions as a substrate-specific adapter of the CUL-3 ubiquitin ligase.
Nature, 425, 311-316.

Pintard, L., Kurz, T., Glaser, S., Willis, J.H., Peter, M. and Bowerman, B. (2003)
Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C.elegans.
Curr. Biol. 13, 911-921.

Chang, F., and Peter, M. (2003)
Yeasts make their mark.
Nat. Cell. Biol., 4, 294-9.

Lafourcade, C., Galan, J.-M., and Peter, M. (2003)
The F-box protein Rcy1p is required to activate the GTPase Ypt6p during recycling of membrane proteins in yeast.
Genetics, 164, 469-477.