Dr. Sung Sik Lee

Dr. Sung Sik Lee
Dr. Sung Sik Lee

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The development of microfluidic-based assay platforms to quantify chemotaxis in yeast

Single cells use chemotaxis to direct their cytoskeletal polarization and movements to the environment. Yeast cells orient their cytoskeleton along a pheromone gradient to promote cell fusion during mating. However, although the microenvironment of cells dynamically changes in this process, most studies of chemotaxis have focused so far on static pheromone gradients. The aim of my project is thus to quantitatively analyze the response of single cells under dynamic conditions and identify how cells cope with a fluctuating chemotactic microenvironment using microfluidic devices coupled to single cell time-lapse microscopy.

You will find further information on my research external pagehere.

Dr. Sung Sik Lee is also affiliated with ScopeM.

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