Publications

Selection of Recent Papers

Investigating Endocytic Pathways to the Endoplasmic Reticulum and to the Cytosol Using SNAP-Trap.
Geiger R, Luisoni S, Johnsson K, Greber UF, Helenius A.
Traffic. 2013 Jan;14(1):36-46.

RNAi screening reveals proteasome- and Cullin3-dependent stages in vaccinia virus infection.
Mercer J, Snijder B, Sacher R, Burkard C, Bleck CK, Stahlberg H, Pelkmans L, Helenius A.
Cell Rep. 2012 Oct 25;2(4):1036-474.

Entry of human papillomavirus type 16 by actin-dependent, clathrin- and lipid raft-independent endocytosis.
Schelhaas M, Shah B, Holzer M, Blattmann P, Kühling L, Day PM, Schiller JT, Helenius A.
PLoS Pathog. 2012;8(4)

Direct identification of ligand-receptor interactions on living cells and tissues.
Frei AP, Jeon OY, Kilcher S, Moest H, Henning LM, Jost C, Plückthun A, Mercer J, Aebersold R, Carreira EM, Wollscheid B.
Nat Biotechnol. 2012 Oct;30(10):997-1001.

Cooperative vaccinia infection demonstrated at the single-cell level using FluidFM.
Stiefel P, Schmidt FI, Dörig P, Behr P, Zambelli T, Vorholt JA, Mercer J.
Nano Lett. 2012 Aug 8;12(8):4219-27.

Single-cell analysis of population context advances RNAi screening at multiple levels.
Snijder B, Sacher R, Rämö P, Liberali P, Mench K, Wolfrum N, Burleigh L, Scott CC, Verheije MH, Mercer J, Moese S, Heger T,
Theusner K, Jurgeit A, Lamparter D, Balistreri G, Schelhaas M, De Haan CA, Marjomäki V, Hyypiä T, Rottier PJ, Sodeik B,
Marsh M, Gruenberg J, Amara A, Greber U, Helenius A, Pelkmans L.
Mol Syst Biol. 2012 Apr 24;8:579.

Oligomers of the ATPase EHD2 confine caveolae to the plasma membrane through association with actin.
Stoeber M, Stoeck IK, Hänni C, Bleck CK, Balistreri G, Helenius A.
EMBO J. 2012 Apr 13;31(10):2350-64.

Cullin-3 regulates late endosome maturation.
Huotari J, Meyer-Schaller N, Hubner M, Stauffer S, Katheder N, Horvath P, Mancini R, Helenius A, Peter M.
Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):823-8.

Histone deacetylase 8 is required for centrosome cohesion and influenza A virus entry.
Yamauchi Y, Boukari H, Banerjee I, Sbalzarini IF, Horvath P, Helenius A.
PLoS Pathog. 2011 Oct;7(10).

BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol.
Geiger R, Andritschke D, Friebe S, Herzog F, Luisoni S, Heger T, Helenius A.
Nat Cell Biol. 2011 Sep 25;13(11):1305-14.

Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture.
Schmidt FI, Bleck CK, Helenius A, Mercer J.
EMBO J. 2011 Jul 26;30(17):3647-61.

Reviews

Gulping rather than sipping: macropinocytosis as a way of virus entry.
Mercer J, Helenius A.
Curr Opin Microbiol. 2012 Aug;15(4):490-9.

Poxvirus host cell entry.
Schmidt FI, Bleck CK, Mercer J.
Curr Opin Virol. 2012 Feb;2(1):20-7.

Endosome maturation.
Huotari J, Helenius A.
EMBO J. 2011 Aug 31;30(17):3481-500

Late-penetrating viruses.
Lozach PY, Huotari J, Helenius A.
Curr Opin Virol. 2011 Jul;1(1):35-43.

Commentaries

Membranes, viruses, detergents, and endosomes.
Helenius A.
Mol Biol Cell. 2012 Nov;23(21):4157-9.

Vaccinia virus egress: actin OUT with clathrin.
Schmidt FI, Mercer J.
Cell Host Microbe. 2012 Sep 13;12(3):263-5.